Withania coagulans Dunal

Withania coagulans Dunal.

Botanical Name:       Withania coagulans Dunal.Withania coagulans Dunal.

Kingdom:                   Plantae

Order:                        Solanales

Family:                       Solanaceae

Genus:                        Withania

Sindhi Name:             Paneer

English Name:           Vegetable rennet, Indian cheese maker

Local Name:               Paneer

Part Used:                  Root, leaves, fruit and seeds

 

Description

WithaniacoagulansDunal.is grey and branched shrub.Shoots are rigid and grey to green. Leaves are leathery and cuneate withfaints nerves. Fruit , a berry, isglobose, broad, and red. Seeds are broad, brown, and somewhat smooth1.

 Occurrence

W. coagulans is distributed to Pakistan, Iran, Afghanistan, and India1.

 Ethnomedicinal Uses in Skin Diseases

Chemical Constituents

Major constituents of W. coagulansare withanine, withaferinA, somniferine, anaferine, pseudowithanine, withananine, somniferinine, and withanolide A. Around 138 withanolides were isolated from this plant. Some other constituents arenicotine, tropine, pseudotropine, 3a-tigloyloxy-tropane, choline, cuscohygrine, dl-isopelletierine and anhygrine2.

Chemical Structure:

Withania coagulans Dunal.st

Medicinal Uses and Pharmacology/Scientific Studies

Fruit of W. coagulans is used for curing digestive and liver complaints3.Its external application is prescribed against inflammatory conditions, ulcers, and scabies4W. coagulans is mixed with ashvagandh powder and oil to make an ointment, used in skin diseases.It act as antidote to scorpion sting5. Chewing oftwigs is recommended for teeth cleaning. Smoke of this plant is also inhaled for getting relief from tooth ache6.

Ethanolic extract of W. coagulans fruit showed anti fungal activity.Leaves and stem showed antibacterial activity1. Withanolides, majore constituent of this plant are reported for various pharmacological actions such as,antimicrobial, anti-inflammatory, antimutagenic,anticancer, anti tumor, diuretic, hepato protective, anti-hyper glycemic, anti hyper lipidemic, cardiovascular, immuno-suppressive, wound healing, anti fungal, antibacterial, free radical scavenging, and depressant activities7.

 References

  1. http://www.efloras.org/florataxon.aspx?flora_id=5&taxon_id=242426281
  2. Jain, R., Kachhwaha, S., and Kothari, S. L. (2012). Phytochemistry, pharmacology, and biotechnology of Withaniasomnifera and Withaniacoagulans: A review. Journal of Medicinal Plants Research, 6(41), 5388-5399.
  3. Bhattacharjee, S. K. (2004), Handbook of Medicinal Plants, p. 378, Pointer Publisher Jaipure 303003 (Raj), India.
  4. Joshi, S. G. (2000), Medicinal Plants, p. 381-382, Mohan Primlani Oxford & IBH Publishers Co. Pvt. Ltd. 66 Janpath, New Delhi 110001, India.
  5. Nadkarins, K. M., Indian MateriaMedica, (1964), p. 1291, Manglore Publishers, India.
  6. http://biosciencediscovery.com/Vol%206%20No1%202015/Debasmita06-13.pdf
  7. http://globalresearchonline.net/journalcontents/v12-2/013.pdf