Vitis vinifera L.
Synonym: Vitis sylvestris
Local Name: Grape
Sindhi Name: Grape
Part Used: Leaves and seeds
English Name: Grape vine
This shrub has stout stem. Its leaves are orbicular, pentagonal /dissected, cordate, irregularly or serrate dentate, acuminate, cordate, and glabrous. Flower are bisexual or functionally pistillate and green in colour,, wiry, elongated and thickened in fruit. Berry differ in shape, size, and color from purple, pinkish, red, black-violet or greenish, 2-4 seeded, with sour or sweet pulp. Seed may be pyriform or ovoid in shape1 .
V. vinifera is cultivated in southern Europe, Western Asia, Iran, Japan, China, Africa, Pakistan, India, Australia, and Afghanistan. In Pakistan it is cultivated mainly in Chitral, Baluchistan, Baltistan, Swat, Astor, and Kashmir1.
Ethnomedicinal Uses in Skin Diseases
Vitis vinifera L. (Grapes) and Sisymbrium irio L. (London rocket) are boiled together in some water, and taken orally for the treatment of measles in District Ghotki (Sindh).
Seeds of grape seeds contain polyphenols (catechin, gallic acid, and epicatechin), flavonoids (quercetin-3-O-glucosides, kaempferol-3-O-glucosides, , myricetin and quercetin) and procyanidins 2,3
Medicinal Uses and Pharmacology/Scientific Studies
Shurb Vitis vinifera L. has been reported to exhibited antimicrobial, anti-inflammatory, antioxidative, antihyperglycemic activities. It is also used for the enhancement of postprandial lipemia, to improve sensitivity of insulin and to prevent hypertriglyceridemia. It also inhibit aromatase activity and protein kinase activity of epidermal growth factor receptor. The leaves are used for the treatment of bleeding, diarrhoea, other circulatory and venous diseases, and haemorrhoids.2,4
- Nassiri-Asl, M., Hosseinzadeh, H. (2009). Review of the Pharmacological Effects of Vitis vinifera (Grape) and its Bioactive Compounds. Phytotherapy Research, 23, 1197–1204.
- Ahmad, W., Khan, M. I., Waqar, M., Khan, M. A., Khan, A., Ramazan, R., Wali, S., Ahmad, F., Khan, N., Yousaf, S., Zeb, M., Khan, A. (2014). In vitro Antibacterial Activity of Vitis vinifera Leaf Extracts against some Pathogenic Bacterial Strains. Advances in Biological Research, 8 (2), 62-67.
- Circus, W., Wharf, C. (2010). Assessment report on Vitis vinifera L., folium. European medicines agency.