Tinospora cordifolia (D.C.) Miers

Tinospora cordifolia (D.C.) Miers

Botanical Name:         Tinosporacordifolia (D.C.) MiersTinospora cordifolia (D.C.) Miers

Kingdom:                    Plantae

Order:                          Ranunculales

Family:                        Menispermaceae

Genus:                         Tinospora

Species:                       T. cordifolia

Urdu Name:                Gilo,Gurach

English Name:             Gulancha, Tinospora

Sindhi Name:              Satgullo

Part Used:                   Stem and root

Description:

Tinospor acordifolia (D.C.) Miers is a tall climber. Stem is smooth, shining, and lenticellate. Bark is light grey in color and papery form. Leaves are long, broadly ovate or orbicular, 7-nerved, subacuminate, young pubescent above, andtomentose beneath. Petiole thickened, twisted, and long. Flowers are greenish yellow in color. Male and female flowers has six sepals in 2 series; outer series has small, ovate-oblong, obtuse, and concave sepals while inner large is suborbicular, membranous, and flat. Petals are subequal,clawed, and smaller than the sepals. Fruit, drupes, are ovoid, smooth, and crimson1.

Occurence:

T. cordifoliais naturalized and cultivated throughout tropical and subtropical regions of Pakistan, India, Burma, and Sri Lanka.

Ethnomedicinal Uses in Skin Diseases

Paste of Tinospora cordifolia (D.C.) Miers (Gulancha) leave is applied on scabies daily in District Sajawal (Sindh). It is also applied on boilsin District Mitiari (Sindh). It is also used for abscess treatment in District Umerkot (Sindh). This paste is also used topically on deep lesion in District Thatta (Sindh). Topical application of this paste is advised for the treatment of fungal infection in District Badin (Sindh).

Scabies:

Paste of T. cordifolialeaves are taken orally with water for one week for curing scabies in District Nawabshah (Sindh).

Wound:

Powder of T. cordifolia leave is mixed with Syzgiumcumini L. (Black pulm) oil to make a paste. It is applied topically for healing wound for 3-4 daysin District Kashmore (Sindh).

Infection and Ringworm

T. cordifolialeaves are used as a bandage and tied on infection in District Karachi (Sindh). This remedy is also prescribed for the treatment of ringworm for 3-5 days in District Thatta (Sindh).

Chemical Constituents:

Root alkaloids were choline, tinosporin, isocolumbin, palmatine, tetrahydropalmatine, and magnoflorine. Furanolactone, octacosanol, heptacosanol, tinosporidine, tinosporon, cordifol, columbin,cordifelone, and nonacosan-15-one were isolated from whole plant. β-sitosterol, d-sitosterol, and 20β-hydroxyecdysone were steroids isolated from aerial part. Ecdysterone, makisterone A, tinocordifolin, cordifoliside A, B, C, D, and E, cordiofoliside, syringin, berberine, palmatine, tembetarine, magnoflorine, and giloinsterol were isolated from stem2.

Chemical Structure:

Tinospora cordifolia (D.C.) Miers.st

Medicinal Uses and Pharmacology/Scientific Studies

The juice of the roots is very much effective in Urinary problems.The whole plant and the juice of the leaves is traditionally used in various mental disorders3.

Stem is stomachic and tonic, stimulates bile secretion, allays thirst, fever, prevents vomiting, cures jaundice, and useful in skin diseases. Juice is useful in diabetes, vaginal and urethral discharges, low fevers, and spleen enlargement. Root and stem in combination with other drugs is used as an antidote to snake bite and scorpion sting. An infusion of the powdered stem is used as an aphrodisiac4.Decoction of stem is used orally for the treatment of fever. Leaf juice is instilled in ears for curing ear pain5.

Potential medicinal properties reported by scientific research include antiallergic, anti-diabetic, antipyretic, antispasmodic, hepatoprotective, anti-inflammatory, antioxidant, antistress, antileprotic, antimalarial, antiarthritic, immuno-modulatory and anti-neoplastic activities6.

References:

  1. http://www.efloras.org/florataxon.aspx?flora_id=5&taxon_id=242352337
  2. Singh, S. S., Pandey, S. C., Srivastava, S., Gupta, V. S., Patro, B., &Ghosh, A. C. (2003). Chemistry and medicinal properties of Tinosporacordifolia (Guduchi). Indian journal of pharmacology, 35(2), 83-91.
  3. http://www.allayurveda.com/herb_month_march2014.asp
  4. Krishna, K ., Jigar, B ., Jagruti, P. (2008). Guduchi (Tinosporacordifolia): Biological and Medicinal properties, a review.The Internet Journal of Alternative Medicine,6(2).
  5. Sinha, K., Mishra, N. P., Singh, J., andKhanuja, S. P. S. (2004). Tinosporacordifolia (Guduchi), a reservoir plant for therapeutic applications: A review. Indian Journal of Traditional Knowledge, 3(3), 257-270.
  6. Upadhyay, A. K., Kumar, K., Kumar, A., & Mishra, H. S. (2010). Tinosporacordifolia (Willd.) Hook. f. and Thoms. (Guduchi) – Validation of the Ayurvedic Pharmacology through Experimental and Clinical Studies. International Journal of Ayurveda Research, 1(2), 112–121.