Psoralea corylifolia Linn.

Psoralea corylifolia Linn.

Botanical Name:     Psoralea corylifolia Linn.Psoralea corylifolia Linn. 

Kingdom:                    Plantae

Order:                          Rosales

Family:                        Leguminosae

Genus:                         Psoralea

Species:                       P. corylifolia

Sindhi Name:              Babchi

Local Name:                Babechi, Bauchi

English Name:             Babchi seeds, Malay tea, Scurf-pea, Fountain bush

Part Used:                   Whole plant

Description

PsoraleacorylifoliaLinn.is an erect, annual, and tall. Stem are pubescent and brown punctate. Leaves are alternate and unifoliolate. Petiole and rachis are long. Lamina are long, broad, cordate, subovate rarely ovate, margin dentate, subtruncate, mucronate, and nigro-punctate on both sides. Inflorescence is a peduncled raceme. Three flowers are present in the axil of each bract. Fruit are ovoid, glabrous, black, pitted, and mucronate1.

Occurance

P. corylifoliais widely distributed in the plains of India, tropical and subtropical regions of the World, especially China, and Southern Africa.In Pakistan, it is widely distributed, especially in coastal area of Baluchistan, Peshawar, and Jhelum.

 

 Ethnomedicinal Uses in Skin Diseases

PsoraleacorylifoliaLinn.(Babchi) seeds is ground and mixed with oil to make a paste. It is applied on white spots for 2 months for the treatment of vitiligoin District Larkana (Sindh).

 Chemical Constituents

 Bakuchiol2, corylifolean, corylifolin, corylifolinin, bakuchicin, psoralidin, isopsoralidin, bavachin, bavachinin, bavachalcone, bavachromanol, corylin, corylidin, corylinal, astragalin, pstigmasterol, triaconate, β-sitosterol-D-glucoside, neobavaisoflavone, bavachromene, bakuchalcone, psoralone, isopsoralone, psoralenol, and psoralidin-2,3-oxide diacetate were found in the seeds3. Essential oil contains γ-elemene, β-caryophylenoxide, geranylacetate, psoralen, angelicin, and bakuchiol. Raffinose, psoralen, and isopsoralen were isolated from leaves. Corylinal and neobavaisoflavonewere isolated from fruit3.

Chemical Structure:

Psoralea corylifolia Linn..st

Medicinal Uses and Pharmacology/Scientific Studies:

All parts of P. corylifolia are used in the treatment of skin problems, such as leukoderma, skin rashes, infections, and others.  Furanocoumarins, which contain psoralens, help in promoting pigmentation3. Its powder is used internally for leprosy and leukoderma, while paste, prepared in water, is applied topically as an ointment. Seeds are employed in scorpion-sting and snake bite4,5. Plant is used in the inflammatory diseases, muco-membranous disorders, dermatitis, and edematous conditions of the skin6. It has blood purifying properties. It is used in the treatment of skin diseases such as, itching red papules, itching eruptions, extensive eczema with thickened dermis, ringworm, rough, discolored dermatosis, boils, dermatosis with fissures, and scabies7. P. corylifolia is reported for antitumor, antihyperglycemic, antidepressant, and antioxidant activities8.

P. corylifoliais reported for anthelminthic and antifungal activities.Psoralidin showed antibacterial activity. Fruits contain bavachinin A that possessed anti-inflammatory, antipyretic, and mild analgesic properties. Bakuchiol, an active constitue of this plant, possess hepatoprotective activity. Bakuchiol, isobavachin, and isobavachalcone showed antioxidant activities. Isobavachalcone and neobavaisoflavone isolated from methanolic extract of seeds inhibited the aggregation of platelets3.

References:

  1. http://www.efloras.org/florataxon.aspx?flora_id=5&taxon_id=200012290
  2. Krishnamurthi AK, Manjunath BL, Sastri BN, Deshaprabhu SB, Chadha YR. Vol. 7. New Delhi: CSIR; 1969. The Wealth of India: Raw Materials; pp. 295–8.
  3. Khushboo, P. S., Jadhav, V. M., Kadam, V. J., & Sathe, N. S. (2010). Psoralea corylifolia—“Kushtanashini.” Pharmacognosy Reviews, 4(7), 69–76. http://doi.org/10.4103/0973-7847.65331
  4. Panda H. New Delhi: National Institute of Industrial Research; 2000. Herbs, Cultivation and Medicinal Uses; pp. 479–81.
  5. Nadkarni KM. Vol. 1. Mumbai: Popular Prakashan Pvt. Ltd; 1976. Indian Materia Medica; pp. 1019–22.
  6. Sharma PC, Yelne MB, Dennis TJ. Vol. 2. New Delhi: Central Council for Research in Ayurveda and Siddha; 2001. Database on Medicinal Plants used in Ayurveda; pp. 89–93
  7. Khare CP. New York: Springer-Verlag; 2004. Encyclopedia of Indian Medicinal Plants; pp. 384–6.
  8. Steven MC, Russell JM. 2nd ed. USA: CRC Press; 2007. Bioactive Natural Products: Detection, Isolation and Structural Determination; p. 254.