Leptadenia pyrotechnica (Forssk.) Decne.

Leptadenia pyrotechnica (Forssk.Decne.

Botanical Name:                  Leptadenia pyrotechnica (Forssk.Decne.Leptadenia-pyrotechnica1

Kingdom:                              Plantae

Order:                                    Gentianales

Family:                                  Asclepiadaceae

Genus:                                    Leptadenia

Species:                                  L. pyrotechnica                                                  

Local name:                          Khipp

Sindhi name:                        Khipp

English name:                     Broom bush

Parts Used:                          Whole plant

Description:

Leptadenia pyrotechnica (Forssk.Decne. is an erect and leafless shrub. Branches are erect, slender, and green when young while brown when older. Leaves are exstipulate, simple, and sometimes reduced or absent. Flowers are actinomorphic, bisexual, and 2 mm in diameter.1

Occurrence:

L. pyrotechnica is found in tropical Africa, Asia, and Mediterranean region. In UAE, it is found in sandy plain of hills and low dunes in eastern part of Abu Dhabi Emirate, and northern Emirates. In Pakistan, it is widely distributed in the hot sandy deserts of Sindh, Punjab, and Baluchistan.2

 Ethnomedicinal Uses in Skin Disease:

Ringworm and Hand infection

  • Juice of pyrotechnica is used for the treatment of ringworm infection in Districts Umerkot, Badin, Tando Allahyar, Nawabshah, Mirpurkhas, and Sukkur (Sindh).
  • Sap of pyrotechnica is applied on the affected area for the treatment of ringworm in Districts Sanghar, Dadu, and Sajawal (Sindh).
  • Sap of this plant is also used for the treatment of hand infection and ringworm infection in Districts Tandojam, Tando Muhammad Khan, and Jamshoro (Sindh).

Vitiligo

Extracted juice is used for the treatment of Vitiligo in District Ghotki (Sindh).

Constituents:

5-Phenyl-undecane and 6-phenyl-tridecane are the major constituents of L. pyrotechnica. Plant also contains phytol, squalene, taraxerol, cholesterol, campasterol, stigmasterol, and fucosterol. Six flavonoids  which  are found in this plant are: kaempferol-3-O-α-l-rhamnopyranosyl (1′″→6″)-O-β-d-glucopyranoside, kaempferol-3-O-β-d-rhamnopyranosyl (1′″→6″)-O-β-d-glucopyranoside, texasin-7-O-β-d-glucopyranoside, kaempferol-3-O-β-d-glucopyranoside , kaempferol, and kaempferide-3-O-α-l-rhamnopyranosyl (1′″→6″)-O-β-d-glucopyranoside.3,4

Chemical Structures:

Leptadenia-pyrotechnica-Forssk.-Decne.st_1

 

Medicinal Uses and Pharmacology/Scientific Studies:

Roots and fruit extracts of L. pyrotechnica are used against Staphylococcus epidermidis. Smoke of the burnt stems is inhaled for the treatment of rheumatism. Herb is used in antiseptic creams for the treatment of burns and wound. Dried hairs of seeds are used as tinder. Stem is used as diuretic for kidney stones. Fiber of L. pyrotechnica is used as antihistaminic and expectorant. Infusion of the plant along with buttermilk is reported to be beneficial for uterine prolapsed and stomach disorders. Plant sap is applied topically to eczema and other skin disease, and is also given in diabetes.5 L. pyrotechnica is reported for antispasmodic, anti-inflammatory, purgative, antispasmodic, antitumor, antibacterial, diuretic, and urolith expulsion properties. Alcoholic extract is reported to be effective against acetic acid-induced ulcerative colitis.6

References:

  1. Ali, S. I. (1983). “Flora of Pakistan”, 150, 52. Department of Botany, University of Karachi, Karachi.
  2. Munazir, M., Qureshi, R., and Munir, M. (2015). “Preliminary Photochemical Screening of Roots and Aerial Parts of Leptadenia pyrotechnica.” Pakistan Journal of Botany, 47(2).p: 659-664.
  3. Moustafa, A. M. Y., Khodair, A. ., and Saleh, M. A. (2009). “Isolation, Structural Elucidation of Flavonoids Constituents from Leptadenia pyrotechnica and Evaluation of their Toxicity and Antitumor activity”. Pharmaceutical Biology,47(6). p:539-552.
  4. Moustafa, A. M. Y., Khodair, A. I., and Saleh, M. A. (2007). “Phytochemical Investigation and Toxicological Studies of Lipid Constituents Isolated from Leptadenia pyrotechnica”.Journal of Pharmacological and Toxicological, 2 (8). p: 681-697.
  5. Verma, N., Jha, K. K., Chaudhary, S., Singh, O., and Kumar A. (2014). “Phytochemistry, Pharmacology and Traditional Uses of Leptadenia pyrotechnica– An Important Medicinal Plant”. Indian Journal of Pharmaceutical and Biological Research. 2(1). p:128-134.
  6. Khasawneh, M. A., Elwy, H. M., Hamza, A. A., Fawzi, N. M., and Hassan, A. H. (2011). Antioxidant, Anti-Lipoxygenase and Cytotoxic Activity of Leptadenia pyrotechnica (Forssk.) Decne Polyphenolic Constituents. Molecules. 16 (9). p:7510-21.