Glinus lotoides L.

 Glinus lotoides L.

Botanical Name:          Glinus lotoides L.Glinus lotoides L.

Kingdom:                        Plantae

Order:                              Caryophyllales

Family:                            Molluginaceae

Genus:                             Glinus

Species:                          G. lotoides

Sindhi Name:               Kotak

Local Name:                 Kothuk

English Name:             Lotus sweet juice

Parts Used:                   Whole plant

Description:

Glinus lotoides L. is an annual procumbent herb with stellate woolly parts. Leaves are sub-verticillate, long, broad, and often mucronate. Flowers are present in axillary clusters of 5-6, sub-sessile, and have long pedicel. Seeds are very small and tuberculate with a curved linear appendage1.

Occurence:

G. lotoidesis distributed in most tropical parts of the world including Ceylon, Africa, India, and Pakistan.

Ethnomedicinal Uses in Skin Diseases (Sindh):

Roots of Glinus lotoides L. (Lotus sweet juice) is ground with some water to make a paste. It is applied topically for the treatment of pyoderma in District Thatta (Sindh).

Chemical Constituents:

Glinusides F, G, H, and I, succulentoside B, vicenin-2, and vitexin-2′′-O-glucoside were isolated from the seeds of Glinus lotoides2. Mollugogenols A, B, C, D, and E,β- and γ-sitosterol glucosides,oleanolic acid,mollugogenol a-3, mollugogenol-7, stidmollugogenol-F, and 3β,16β,22-trihydroxyisohopane were isolated from different parts of plant3.

Chemical Structure:

 Glinus lotoides L.st.

Medicinal Uses and Pharmacology/Scientic Studies:

Herbof G. lotoidesis given as purgation in abdominal diseases. Dried plant is employed in diarrhoea. It is also applied locally on skin ailments and pruritus. Seedsare used in the treatment of tapeworm infestation. Juice of the plant is recommended to weak children for strength3.

G. lotoides is widely used by scientist for research purpose and reported for a number of biological activities. It includes Anti-spasmodic4,anti-ulcerogenic5, Molluscicidal6, Wound healing7, and antioxidant8 activities. Seeds of G. lotoides were found to chemopreventive due to the presence of some nutritional compounds such as, vitamin E, folic acid, selenium, and calcium9. Methanol and n-hexane extracts induced significant apoptosis in the cancer cells10.

References:

  1. http://www.efloras.org/florataxon.aspx?flora_id=5&taxon_id=220005631
  2. Endale, A., Wray, V., Murillo, R., Schmidt, P. C., & Merfort, I. (2005). Hopane-type saponins from the seeds of Glinus lotoides. Journal of natural products, 68(3), 443-446.
  3. Bhavani. Glinus lotoides (Ciru-Ceruppadai): An overview ,Journal of Chemical and Pharmaceutical Research, 2015, 7(8):676-682
  4. Toxicological study on Glinus lotoides:Atraditionally used taenicidal herb in Ethiopia/Demma et al .Journal of Ethnopharmacology,Vol.111,issue 3,22 may 2007pg 451-457.
  5. Bioscreening of herbs with putative anyi-ulcerogenic activity in rats by Amna Ehlasan Hamad Mohamed.
  6. Laboratory assessment of molluscicidal and cercariacidal effects of Glinus lotoides fruits.,GebrehiwotKiros,Berhanu Erko,Mitutse Giday and Yalemtschay Mekonnen.
  7. Sudha Rameshwari et al; Int J. Pharm. Bio Sci2013Oct; 4(4):(P) 722-728.
  8. J Demma, H El-Seedi, E Engidawork et al;Phytotherapy2013.
  9. Anti-cancer activity of extracts of the seed of Glinus lotoides,Mengesha AE,Youan BB,KJ Nutri Sci vitaminol(Tokyo) 2010;56 (5):311-8
  10. Mengesha AE,Youan BB,KJ Nutri Sci vitaminol(Tokyo) 2010;56 (5):311-8