Fagonia arabica L.

Fagonia arabica L.

Kingdom:                    PlantaeFagonia arabica L.

Order:                          Zygophyllales

Family:                        Zygophyllaceae

Genus:                          Fagonia

Specie:                          F. arabica

Urdu Name:                Dhamasa, suchi buti

Sindhi Name:              Daramaho

English Name:           Cretan prickly clover

Part Used:                   Whole plant

 

Description:

Fagonia arabica L. is shrublets and perennial. Lower leaves are trifoliolate while upper leaves are unifoliolate. Petioles and stipular spines are long. Leaflets are linear to oblong and mucronate. Sepals are deciduous, oblong to lanceolate,and glandular outside. Petals are obtuse while Stamens are long. Capsules are glandular-pubescent1.

 Occurances:

Fagonia arabica L. is globally distributed in Africa, Arabia, Pakistan and India.

 Ethnomedicinal Uses in Skin Diseases (Sindh):

Fagonia arabica L. is boiled in some water and then sieved.  This water is used for purposes;

  1. Water is used for taking bath for the treatment of scabies for 5-7 days in DistrictsNawabshah, Tando Muhammad Khan, Mirpurkhas, Sanghar, Tharparkar, Nausheroferoz, Ghotki, Khairpur, and Matiari (Sindh).
  2. This water is also used for washing the area affected with furuncles in District Badin (Sindh).
  3. This water is used for taking bath for the treatment of prickly heat for one week in District Nawabshahand Tando Jam (Sindh).
  4. This water is also used for washing wounded area in District Karachi (Sindh).
  5. This water is used for taking bath for the treatment of ringworm in District Umerkot (Sindh).

Scabies and itching

F. arabicais boiled in some water and then sieved. This water is taken orally for 3-4 daysfor curing scabies in District Ghotki (Sindh). The same remedy is used orally for the treatment of itching in District Sukkur (Sindh).

 Pyoderma:

Gonadl*, F. arabica, crystal sugar, and Nigella sativa L. (Black cumin) are boiled in some water. This water is taken orally for the treatment of pyodermain District Kashmore (Sindh).

Ringworm:

Leaves of F. arabicais ground to make paste and applied on ringworm in District Nawabshah (Sindh).

Chemical Constituents:

The triterpenoid saponins isolated and their structure established from arial parts are 23,28 –di-o-beta-D-glucopyranosyl-taraxer-20-en-28-oicacid.Quercetin and kaempferol from leaves &

flowers.Docosyl docosanoate, ceryl alcohol, setostirol,and n-tricontanol chenovic acid

were isolateted from hydrolsed plant extract. Plant extract showed presence of

fagogenin and chenovic acid. Fagogenin,Genin A, C, andB, stigamastirol,and kaempferol. The fruits are rich in ascorbic acid2.

Chemical Structure:

Fagonia arabica L.st

 

Medicinal uses and Pharmacology/Scientific studies:

Infusion ofariel part is effective as a cooling agent in stomatitis andforblood purification. It also acts as deobstruent. It is also used for skin diseases such as, small pox. Twigs are used for snake bite and its paste is applied externally on tumours and neck swellings. Decoction of dried leaves or fresh juice of whole plant is used in stomach problems,fever, and skin problems generally itching, and wounds2.

Ethanol extract showed antimicrobial activity. Alcoholic activity possessed analgesic activity. Shoot powder is reported for antioxidant activity3.Plant possesses thrombolytic properties4.

Methanolic extract of whole plant is reported foranti-inhibitory activty for hormone sensitive lipases5 and pancreatic lipase inhibitoryactivity6.

Aqueous and ethanol extracts were found as aphids repellent. Different extracts from aerial parts exhibited varying degree of molluscidial activity. Acetone extracts were found effective against Helicobacter pylori related diseases.Aqueous extract also exhibited antibacterial activity7.

References:

  1. http://efloraindia.nic.in/efloraindia/taxonList.action?id=2825&type=4
  2. Kasture, V. S., Gosavi, S. A., Kolpe, J. B., & Deshapande, S. G. (2014). Phytochemical and Biological Evaluation of Fagonia Species: A Review.
  1. Pareek, A., Batra, N. & Goyal, M. (2012). Phytochemical and Biological Activity of Fagonia indica. International Research Journal of Pharmacy, 3(6), 56.
  1. Prasad, S., Kashyap, R. S., Deopujari, J. Y., Purohit, H. J., Taori, G. M., and Daginawala, H. F. (2007). Effect of Fagonia Arabica (Dhamasa) on in vitro thrombolysis.BMC Complementary and Alternative Medicine7(1), 1.
  2. Yasser, B., M, Mohammad., Mohannad, H., (2011). ‘Hormone sensitive lipase inhibition by selected medicinal plants’ Journal of Medicinal Plants Research Vol. 5(18), pg 4405-4410.
  3. Yasser, B., M,Mohammad., Mohannad, H., TawahaKhaled, Al-MasriIhab, M., AlKhatibHatim, S., IssaAla, AlaliFeras, Q., (2011). ‘Screening of some medicinal plants for their pancreatic lipase inhibitory potential, Jordan Journal of Pharmaceutical Sciences, Volume 4, No. 2.
  4. Hussein M. A., Gupta, S. K. (2014). Review of Ethnomedicinal Plant Fagonia, International Journal of Pharmaceutical Applications, 5(2), 22-28.