Datura stramonium L.

Datura stramonium L.

Botanical Name:         Datura stramoniumL.Datura stramonium L.

Synonym:                      Daturabernhardii,

                                           Daturacapensis,

                                           Stramoniumfoetidum,

                                           Stramoniumtatula,

                                           Stramoniumvulgare

Kingdom:                      Plantae

Order:                            Solanales

Family:                          Solanaceae

Genus:                           Datura

Local Name:               Datura

English Name:           Thorn apple

Sindhi Name:             Datooro

Part Used:                   Inflorescence and pods

 

Description

Daturastramonium L. is a plant with extremely unpleasant smell. Branches are forms a bushes up to 2 to 5 ft high1. Stem is long and thick while root is white in color and fibrous. Leaves are pointed and have a wavy outline. Flowers growin summer. Seed capsule is covered with spines2.

Occurrence

D. stramonium is native to North America and widely distributed in Mexico, Australia, Pakistan and India.

Ethnomedicinal Uses in Skin Diseases

Pyoderma:

Datura stramonium L. (Jimson Weed) plant is crushed and mixed with butter to make a paste and applied on the affected area for curing pyoderma District Badin (Sindh).

Abscess:

  1. Paste of Ziziphus numularia L. (Chinese Apple) and D. stramonium leaves is applied on the abscess affected area in District Khairpur (Sindh).
  2. Leaves of D. stramonium leaves are tied on the affected are for curing abscess in Districts Mitiari and Khairpur (Sindh).
  3. Paste of Dalbergi sissoo Roxb. (North Indian Rosewood) and D. stramonium leaves is used for the treatment of abscess in District Nausheroferoz (Sindh).

Onchomycosis:

D. stromonium leaves are ground and mixed with Triticum aestivum L. (Wheat) flour, this paste is applied on the affected area for the treatment of fungal infection in District Nawabshah (Sindh).

Infection:

Paste of D. stromonium leaves is applied on the chronic infection daily in District Sukkur (Sindh).

 ChemicalConstituents

Hyoscyamineand scopolamine are major constituents of this plant. Alkaloids such as, tigloidin, aposcopolamine, hyoscyamine N-oxide, apoatropin, 3-phenylacetoxy-6, 7-epoxynortropane, scopolamine N-oxide,tropinone, scopine, 7-hydroxyhyoscyamine, phenylacetoxytropane,hygrine,6-hydroxyhyoscyamine,pseudotropine, hyoscyamine, littorine, tropine, 3-acetoxytropane, aponorscopolamine,7-hydroxyapoatropine, and 7-hydroxyhyoscyamine are also present3.Hyoscyamilactol, daturadiol, umckalin, cleomiscosin A,daturaolone, and fraxetin were isolated from seeds4.

Chemical Structure:

Datura stramonium L.st

Medicinal Uses and Pharmacology/Scientific Studies

Leaves extract of D. stramonium is administrated orally in asthma and sinus infections.Bark is applied to the swellings, skin burns, and ulcers, externally.Plant is also used in treating dental and skin infections, hair fall (alopecia), and toothache.Ointment prepared from this plant is applied on burn area and rheumatism. Roasted leaves are applied for getting relieve from pain. Juice is massaged on scalp to get rid of dandruff and falling of hair. Seeds is used as poultice in treating abscesses wound and neuralgia. Its berries are poisonous and lead to the dead if taken orally3.

D. stramonium is reported for antiepileptic,antiasthmatic, acaricidal, repellent, bactericidal, antifungal, anti-inflammatory,andanticanceractivites. The plant is strickly prohibited during pregnancy5.

References

  1. Henkel, Alice (1911). Jimson weed.American Medicinal Leaves and Herbs.S. Government Printing Office. p. 30.
  2. Grieve, M. (1971).A Modern Herbal: The Medicinal, Culinary, Cosmetic and Economic Properties, Cultivation and Folk-lore of Herbs, Grasses, Fungi, Shrubs, & Trees with All Their Modern Scientific Uses, 2, 804, Dover Publications.
  3. Soni, P., Siddiqui, A. A., Dwivedi, J., andSoni, V. (2012). Pharmacological properties of Daturastramonium as a potential medicinal tree: An overview. Asian Pacific Journal of Tropical Biomedicine, 2(12), 1002–1008. http://doi.org/10.1016/S2221-1691(13)60014-3.
  4. Li, J., Lin, B., Wang, G., Gao, H., and Qin, M. (2012). [Chemical constituents of Daturastramonium seeds]. ZhongguoZhongyaozazhi= Zhongguozhongyaozazhi= China journal of Chinese materiamedica, 37(3), 319-322.
  5. http://www.jcimjournal.com/articles/publishArticles/pdf/jintegrmed2013016.pdf