Aloe Vera

 

 

Aloe vera (L.) Burm.f.
Kingdom:                      PlantaeAloe vera (L.)Burm.f.

Botanical Name:       Aloe vera (L.) Burm.f.

Order:                           Asparagales

Family:                         Xanthorrhoeaceae

Genus:                          Aloe

Local Name:                  Aloe

Sindhi Name:                 Alva

English Name:               Aloe vera

Parts Used:                    Leaves and roots

Description

Aloe vera (L.) Burm.f. is a perennial plant. Stem is very short and growing up to 60–100 cm . Leaves are sessile, thick,green,and fleshy with serrated margins having small white teeth. Leaves have three layers. Flowers are yellow and long with tubular corolla1,2.

Occurrence

A. verais originated in the Sudan. Itwidely distributed in Africa, Australia, Mexico, china, south America, central America, India, Pakistan, Nepal, and other arid areas1,2.

Ethnomedicinal Uses in Skin Diseaes:

Scabies:

  1. Aloe vera (L.)Burm. f. (Aloe vera) gel is applied topically for the treatment of scabies in District Shikarpur (Sindh). It is also used externally for the treatment of ringworm in District Khairpur (Sindh).
  2. A. vera herb and Linum usitatissimum L. (Flex Seed) seeds are ground together to make a paste, and applied topically for the scabiesin District QamberShahdadkot (Sindh).

Wound

  1. A. vera gel, karwa oil, sulfur,TriticumaestivumL. (Wheat) flour, jaggery, and Allium cepa L. (onion) are ground together to make a paste. It is applied externally for healing wounds in District Kashmore (Sindh).
  2. Leaves ofA. vera is tied on wound in District Tando Jam (Sindh).

Pyoderma

Leaves ofA. vera is ground to make a paste and then applied on wound and for the treatmemt of pyoderma in District QamberShahdadkot (Sindh).

Atopic dermatitis:

A. veragel is applied topically daily for the treatment of atopic dermatitis in District Kashmore (Sindh).

Acne:

A. veragel is massaged on face for the treatment of acne in District Tharparker, QamberShahdadkot, and Khairpur (Sindh).

Boils and Otitis externa

A. veraleaves with gel is ground and applied topically on face for 3-4 times a day till recovery for the treatment of boils in District Tando Muhammad Khan (Sindh).this remedy is also used topically for the treatment of otitis externa in District QamberShahdadkot (Sindh).

Burn

A. veragel is applied topically on burnt area in District Larkana and QamberShahdadkot (Sindh).

Blood blisters

A. veragel, Curcuma longa L. (Turmeric) powder, and salt are mixed, and then heated. It is applied on blisters in District QamberShahdadkot (Sindh).

 Chemical Constituents

A. veracontains anthraquinones, vitamins, minerals, enzymes, amino acids, fatty acids, sterols,and polysaccharides. Anthraquinones includes aloe-emodin, aloetic-acid, anthranol, aloin A and B,isobarbaloin, emodin, and ester of cinnamic acid3. It also contains cholesterol, campesterol, β-sisosterol, and lupeol4.Vitamins such as β-carotene, thiamine, riboflavin, choline, and folic acid are also present2.

Chemical Structure:

Aloe vera (L.)Burm.f.st.

 

Medicinal Uses and Pharmacology/Scientific Studies

Gel of A.vera is widely used for medicinal purpose for the treatment of various diseases either applied externally or internally. It is used for getting rid of dandruff and used for the treatment of osteoarthritis, lungs cancer, diabetes, ulcer, heart burn, genital herpes, constipation, obesity, asthma, epilepsy, and cardiovascular5.It is also applied topically on skin pigmentation, sebaceous cyst, skin eruption, scalp,burns,itching, blisters, skin aging, acne, and for glowing and fresh skin6,9.

Anthraquinones,active class of compound of A. vera,is responcible for antimicrobial properties against Mycobacterium tuberculosis, bacillus subtilis, staphylococcus aureusstreptococcus pyogenes, and salmonella paratyphi8. Aloe juice is effective against pathogenic fungi such as Aspergillusniger and Candida9.Plant is reported foranti-fungal,immune-stimulation, anti-inflammatory, wound healing, promotion of radiation damage repair, antibacterial, antiviral, and antioxidant activities6. Leaves of A. verashowed hypoglycemic, hypolipidemic, and antimutagenic activities7.

References

  1. https://en.wikipedia.org/wiki/Aloe_vera
  2. Kumar, S., andYadav, J. P. (2014). Ethnobotanical and pharmacological properties of Aloe vera: A review.Journal of Medicinal Plants Research, 8(48), 1387-1398.
  3. Chatterjee, P., Chakraborty, B., andNandy, S. (2013). Aloe veraplant: Review with significant pharmacological activities.Mintage journal of pharmaceutical and Medical Sciences, 2(3), 21-24.
  4. Sahu, P. K., Giri, D. D., Singh, R., Pandey, P., Gupta, S., Shrivastava, A. K., andPandey, K. D. (2013). Therapeutic and medicinal uses of Aloe vera: a review.Pharmacology & Pharmacy, 4(08), 599.
  5. Qadir, M. I. (2009). Medicinal and cosmetological importance of Aloe vera. Int J Nat Ther,2, 21-26.
  6. Reynolds, T., andDweck, A. C. (1999). Aloe vera leaf gel: a review update. Journal of ethnopharmacology,68(1), 3-37.
  7. Kim, K., Kim, H., Kwon, J., Lee, S., Kong, H., Im, S. A., and Park, Y. I. (2009). Hypoglycemic and hypolipidemic effects of processed Aloe vera gel in a mouse model of non-insulin-dependent diabetes mellitus. Phytomedicine,16(9), 856-863.
  8. Athiban, P. P., Borthakur, B. J., Ganesan, S., andSwathika, B. (2012). Evaluation of antimicrobial efficacy of Aloe vera and its effectiveness in decontaminating guttapercha cones.Journal of conservative dentistry, 15(3), 246.
  9. Kedarnath, K. K. M., Chimkod, V. B., andPatil, C. S. (2013). Antimicrobial Activity of Aloe Vera Leaf Extract.International Journal of Applied Biology and Pharmaceutical Technology.